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however, it also resulted in an undesired elevation in the controlled attenuation parameter (evaluating LFC)

Reviews To Read February 2026 Published in JAMA Psychiatry by Mehdi Farokhnia and Lorenzo Leggio of the NIDA IRP Clinical Psychoneuroendocrinology and Neuropsychopharmacology Section

At the 12 mg dose in the phase 2 trial, adults with type 2 diabetes achieved approximately 16.9% mean body weight reduction and around 2.2 percentage point HbA1c reduction at 24 weeks

Conclusion This comprehensive review highlights the therapeutic potential of GLP-1 and its analogs in the management of metabolic disorders, particularly T2DM