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We collected plasma samples for each patient from EDTA-anticoagulated tubes, taken as part of routine biological check-ups according to the department protocol, at three time points: preoperatively, immediately postoperatively in the intensive care unit, and on the first postoperative day

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The mobile phase A was 0.1% formic acid in water, while the mobile phase B was 0.1% formic acid in water-acetonitrile solution (containing 95% acetonitrile)

It plays a vital role in tissue repair, anti-inflammatory signaling, and metabolic balance