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but lower doses led to more modest weight loss:Lower doses had a more favourable side effect profile, too:This triple agonism aims to relieve some of the side effects of GLP1s (nausea, muscle loss), and increase weight loss (so the dose can be lowered)Sources: New obesity drugs - nature.com/articles/d4158 Triple agonist Retatrutide phase 2 trial - nejm.org/doi/full/10.10 full article: openread.academy/en/paper/readi Breakdown of the article: The article discusses the development of new obesity drugs that aim to provide greater and healthier weight loss

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No cases of pancreatitis or thyroid malignancy were reported during the trial period, though these remain areas of ongoing surveillance given their association with this drug class

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Interest in advanced weight-loss and metabolic research compounds has grown rapidly in recent years, and retatrutide is now at the centre of that discussion

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