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Here are the most common symptoms of the major gastrointestinal problems associated with Saxenda use: Frequent nausea Excessive vomiting Acid reflux (GERD) Severe abdominal discomfort Bloating or swelling of the abdomen Loss of appetite Lack of bowel movements What to Do If You Experience Gastrointestinal Complications from Saxenda Use If you or a family member has experienced any of the symptoms listed above, seek immediate medical attention