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Monitoring Response Patients or research participants typically notice: Appetite suppression within the first 12 weeks Early satiety and slower gastric emptying by weeks 34 Weight loss trends becoming evident by week 8 Continued improvements in glucose metabolism when paired with semaglutide or tirzepatide Side Effects and Considerations Common side effects include: Nausea Mild gastrointestinal discomfort Constipation Injection site reactions These effects are generally transient and dose-dependent, which is why titration is important

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The Prohibited List is updated annually and comes into effect on 1 January every year, and any changes to the Prohibited List are made public every year in early October for changes applicable to the upcoming year

doi: 10.1016/j.thromres.2020.04.013 145 KnollR.SchultzeJ