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Taiwan Journal of Physical Medicine and Rehabilitation, 47(1), 2129.

Successful application of acid labile linkers requires advanced chemical design, conjugation strategies, and production capabilities

In addition to performing several important functions in the human body (e.g., participating in collagen biosynthesis [94], l-ascorbic acid plays a significant role as a component of the ascorbate peroxidase enzyme found in some plants, which protects them from the effects of free radicals resulting, for example, from photosynthesis or photorespiration [95]

Both have intriguing preclinical profiles but very limited human clinical data