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06 Fiber and bowel changes Fiber and bowel changes Constipation is common enough during GLP-1 treatment that fiber, water, movement, and bowel changes are worth tracking

In this paper we draw from human electronic medical records, rodent behavioral studies, and single cell RNA sequencing to uncover a role for endogenous sex hormone signaling in mediating the differences in efficacy and tolerability between sexes that are observed with GLP1R agonists

[14] GLP-1 agonists already cause nausea, vomiting, and gastroparesis-like symptoms in a meaningful proportion of patients