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In our self-controlled design, no evidence of increased risk of suicide or suicide attempts following GLP-1 RA initiation was observed, consistent with a French case-time-control study including 1102 patients with suicide attempt or fatal suicide and 5,494 controls from 2013-2021 [31]

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Evidence suggests that DPP-4 inhibitors reduce urinary albumin excretion, oxidative stress, and renal dysfunction in patients with T2D independent of their glucose-regulatory activity [117, 118]